The fundamentals of cell and molecular biology are provided during this course. Topics include cell composition, structure of DNA and RNA, RNA transcription, protein synthesis, cell signaling, cell death.
Topic: The Biology Behind Disease
Tumour Microenvironment
This module will cover the importance of the tumour microenvironment and tumour physiology in regulating oxygen sensing mechanism, angiogenesis and blood vessel stability. The students will learn the importance of the tumour microenvironment in regulating the function and maturation of…
Therapeutic targeting of cellular instability in childhood and adult cancers
This module will cover in detail the importance of how cellular damage drives different forms of cellular instability. The students will be taught about how different forms of damage affect telomere length dysfunction, activation of the bridge breakage fusion cycle…
Cancer Epigenetics, Gene Regulation and Stem Cells
This module will provide a solid foundation in the area of chromatin structure and the principles of epigenetics. Lectures will detail the covalent modifications of DNA and histones, the techniques used to determine epigenetic modification, and the principles and experimental…
Tumour Immunology
The aim of this module is to provide a fundamental understanding of important immunological concepts and how they apply to the field of tumour immunology and immunotherapy. The module will explore how both the innate and adaptive immune system recognises…
Disease-Specific Cancers: Scientific and Clinical Perspectives
This module aims to provide a fundamental understanding of both the scientific and clinical aspects of site-specific malignancies. It is becoming increasingly evident that the abnormal profile of cancer cells with respect to dysregulation of cellular processes and genetic abnormalities…
Cellular and Molecular Basis of Cancer
The aim of this module is to give the student a broad introduction to the cellular and molecular basis of cancer. The module explores the molecular and cellular hallmarks of cancer, including cell cycle, apoptosis, DNA repair mechanisms, angiogenesis and…
Cell Signalling and Molecular Medicine
This module is designed to give postgraduate students and early career researchers a solid understanding of cell signaling mechanisms relevant to disease pathogenesis and therapeutic development and to overview commonly used techniques and approaches for their analysis. This course is…
Inflammation: from Cell to Clinic
This module will provide an in depth introduction into how we can manipulate the inflammatory/immune response and their interaction with microbes to identify, modify and prevent disease. Lectures will provide a basic overview of common models used, key areas of…
The immune system in health and disease
This module in Immunology in Health and Disease will provide an in depth knowledge of the human immune system covering surveillance and the role of immunity in homeostasis, fighting infection and dysregulation leading to disease. Students will develop an understanding…