This module will cover in detail the importance of how cellular damage drives different forms of cellular instability. The students will be taught about how different forms of damage affect telomere length dysfunction, activation of the bridge breakage fusion cycle…
Curriculum: ICAT
Tumour Microenvironment
This module will cover the importance of the tumour microenvironment and tumour physiology in regulating oxygen sensing mechanism, angiogenesis and blood vessel stability. The students will learn the importance of the tumour microenvironment in regulating the function and maturation of…
Clinical Pharmacology and Therapeutic Toxicity
This module will provide both scientists and clinicians with an in-depth knowledge of the major families of chemotherapeutic drugs currently in use to treat a range of solid and haematological malignancies. These lectures will describe the mode of action, clinical…
Drug Development Process from Discovery to Commercialization
This module will cover in-depth, the principles of the drug discovery process and how it depends on molecular pharmacology and medical chemistry to identify new drug targets. The students will also learn the different experimental screening methods used to identify…
Molecular Pathology and Diagnostic Imaging
The aim of this module is to provide the student with an overview in the area of molecular pathology and diagnostic imaging. Modern cancer research and cancer medicine are dependent on an understanding of pathology, including tumour classification, staging and…
Clinical Statistics and Medical Ethics
The aim of part I of this module is to provide a fundamental understanding and practical experience with statistics. The statistics part of this module will be run as a two day statistics workshop, covering descriptive statistics, study design and…
Cancer Epigenetics, Gene Regulation and Stem Cells
This module will provide a solid foundation in the area of chromatin structure and the principles of epigenetics. Lectures will detail the covalent modifications of DNA and histones, the techniques used to determine epigenetic modification, and the principles and experimental…
Tumour Immunology
The aim of this module is to provide a fundamental understanding of important immunological concepts and how they apply to the field of tumour immunology and immunotherapy. The module will explore how both the innate and adaptive immune system recognises…
Cellular and Molecular Basis of Cancer
The aim of this module is to give the student a broad introduction to the cellular and molecular basis of cancer. The module explores the molecular and cellular hallmarks of cancer, including cell cycle, apoptosis, DNA repair mechanisms, angiogenesis and…
Disease-Specific Cancers: Scientific and Clinical Perspectives
This module aims to provide a fundamental understanding of both the scientific and clinical aspects of site-specific malignancies. It is becoming increasingly evident that the abnormal profile of cancer cells with respect to dysregulation of cellular processes and genetic abnormalities…